Relic and THQ recently announced a sequel to the popular Warhammer 40k RTS. I really enjoyed Dawn of War, and although I haven't played any of the expansions, I'd say this game that appears to be built on the bones of Company of Heroes shows a lot of promise. The few screens available look great, and you can see the echoes of CoH in there. I'm not a 40k fanboy, but there's just something compelling about Marines vs. Orks -- vs. a thousand other factions, of course. View the teaser trailer here.
Ah, so reading more, apparently Warhammer 40k II debuts the Essence Engine 2.0 -- no wonder the screens look like Company of Heroes.