Greg and I tore up Shards of Orr last night. I went with the triple Smiter build (hit OwAT0GHD5xkwPQJVfXC1/jETAA in your template manager for the details) on my trio of monk heroes, and Signet of Judgement, among other things, just ripped apart undead mobs. Greg's Spoil Victor helped, too. I used Sight Beyond Sight to protect against the silly blinds that the wizards use all the time. Annoying.
For my troubles, I got crap drops, but I did get my entry in the Master Dungeon Guide checked off, leaving only Slaver's Exile. We need to make a serious attempt on that place.
Oh, like the new Destroyer Shield?